Sunday, November 23, 2008

Unit Four/Online Lab-Embronic and Fetal Development

EMBRONIC AND FETAL DEVELOPMENT ONLINE LAB


LIST OF TEN SIGNIFICANT EVENTS DURING EMBRYONIC AND FETAL DEVELOPMENTFOR EACH EVENT:


(1)--quick description of what the event is

(2)--when (hour, week, day or month) during development when it occurs
(3)--why you think it is significant--image or photo of that event or stage for five of the events







www.visembryo.com/baby/index.html (web link provided for lab)
(1) Oocyte Fertilized/ Conception occurs-1 day post ovulation-
Penetration by one sperm into the oocyte’s tough membrane, within hours fertilization is complete and the zygote is created with the entire set of genetic make-up complete! This is significant because it is the miracle of life. This is how it ALL begins!


(2) Heart division into two chambers-6 week old fetus-
The baby’s heart beats twice as fast as an adult heart beat and it is starting to divide into two chambers. This is significant because the heart is starting to develop in ways that will last throughout the human lifetime (two chambers in the heart: the left and right ventricles).










www.visembryo.com/baby/index.html (web link provided for lab)

(3) Upper limb buds appear- 25-27 days post-ovulation (first trimester)
During this time the face and neck are starting to take shape and also the eye and ear will begin to form. During this stage the beginning cells of the liver also begin which is the first piece of the digestive system that is yet to come. The significance of this stage is that the limb buds are the beginning of the arms/hands/fingers of the human body.

(4) Hind brain is beginning to develop- 37-42 days (first trimester) The brain is beginning to become defined in the various regions. The hind brain, which is responsible for regulating heart regulation, breathing and muscle movements, begins to develop. The significance of this part of development is the brain and body functions are becoming synchronized to perform functions both voluntarily and involuntarily.






www.visembryo.com/baby/index.html (web link provided for lab)

(5) Spontaneous movement begins-51 - 53 days post-ovulation- Tiny muscles and nerves are connected to the brain and the fetus is able to make spontaneous movements. The significance is that this is the first stage where the unborn fetus can move independently.



(6) End of the embryonic period- 56-60 days post-ovulation- The embryo has now reached the stage of development that it is a fetus. The significance is that development of the ears, eyes, taste buds, teeth, upper palate, intestines, and limbs is well advanced. The “tail” is now gone. The external genitals are still not developed well.


(7) Basic brain structure in place-61-68 days post-ovulation- The brain can rapidly grow from this point on as the brain structure is complete in the fetus. The significance of this stage is that the brain parts are formed now and will continue to grow within the fetus. Another significant event during this same stage is that the facial features of the fetus are distinguishable.






www.visembryo.com/baby/index.html (web link provided for lab)

(8) Sexual organs are clearly visible- 14 week post-ovulation- At this stage the fetus’ sex organs, whether male or female, can be easily seen. Toenails are also starting to grow from the nail beds during this stage.


(9) Finger and toe prints swirls are formed-16 week post-ovulation- The significance of this stage is that the set of prints that makes this individual different than every other individual ever born are starting to be formed on each finger/thumb pad, as well as on the toe pads.







www.visembryo.com/baby/index.html (web link provided for lab)
(10) Immune system begins to develop-32 weeks post-ovulation- At this stage the fetus’ immune system is beginning to develop its defense against germs, virus, and bacteria. The significance of this stage is that the defenses are already being put into place that will help protect the baby after birth. Another fact I find significant during this stage is that the eyes of the fetus can remain open during times of alertness and they shut during times of sleep.

Sunday, November 16, 2008

Compendium Review Unit Four/Major Topic Two:Human Landscapes/Chapters 22,23,and 24

Chapter 22/Human Evolution


22.1 Origin of Life

22.2 Biological Evolution

22.3 Classification of Humans

22.4 Evolution of Hominids
22.5 Evolution of Humans










22.1 Origins of Life


A fundamental principle of biology states, “All living things are made of cells and that every cell



comes from a preexisting cell.” The question presented then is, “Where and how did the very



first living thing come into existence then?” Possibly the answer is that a slow chemical process


change occurred and produced the first cell -protocell/(chemical evolution)


The Solar System developed approximately 4.6 BYA. The Earth has atmosphere. The


atmosphere we have today is quite different than the first atmosphere due to gases and water.


Also heat played a huge role in the atmosphere from long ago.


Primitive Earth had the following energy sources:






1- Volcanoes






2- Meteorites






3- Radioactive Isotopes






4- Lightening






5- Ultra-violet Radiation



Macromolecules- RNA first hypotheses/ states that only macromolecule RNA was necessary to lead to formation of the very first cells.



Protein First Hypotheses/ suggests that amino acids collected together when exposed to dry heat forming portioned then returned to water to form microspheres, which have many of the same properties as cells.




The Protocell- could metabolize but could not reproduce-fermenter because of no free oxygen-if lipids and microspheres become associated a lipid-protein membrane occurs.



The True Cell- a true cell can reproduce and DNA replicates before cell division occurs. Proteins called, “Enzymatics” perform the replication process.














22.2 Biological Evolution


(1)Prokarytic cells are the first true simple cells of life. A feature of the prokaryotic cell is that they lack a nucleus.






(2)Next came the Eukaryotic Cells which do have a nucleus.






(3)Next came multicellularity along with other kingdoms.






Each of these types have their own evolutionary history starting with the very first cell.






Biological Evolution is the process of a species changing through time.






All living things have a common history of origin.






Adaptation is the species ability to survive and reproduce in its environment.






Adaptation is the explanation why there are so many types of living organisms….a particular species adapts to its unique environment.






Common Descent explains the sameness of a species to its ancestors.






Fossils prove evolution because they are the actual remnants of that particular species.






Fossils are 10,000 years or older- up to billions of years old.






“Traces” are remnants or evidence of past life. Traces can be trails, footprints, burrows, worm casts, or petrified droppings. Pieces of bone, plant impressions, species trapped in tree resins are all examples of fossils. Fossils are commonly found in sedimentary stone.






Sedimentation is the process of particle accumulation that forms layering of the Earth’s crust. A layer of sedimentation is called a strata.






When a species dies, it decomposes or is scavenged, so the remains are typically the hard encasement or bone material, which becomes imbedded in the sedimentary stone layer and is then layered over the top of.






Paleontology is the scientific study and discovery of fossils. The term. “Fossil Record” refers to the history of life recorded by fossils. Species have evolved through time so the fossil remains we find are different than the species is today.






Scientifically we know today that life has evolved from the simple to the complex.
Fossil records show the following progression:






1- unicellular prokaryotes






2- unicellular eukaryotes






3-multicultural eukaryotes






Transitional fossils have the characteristics of two species.






Whales are believed to have terrestrial ancestry. The presence of legs in Ambulocetus species










leads to the hypothesis of terrestrial mammals leading to the whale species.






The origins of mammals is well documented through fossilization of species.






(figure 22.4) page 471- The Archaeopteryx had combo of reptilian/bird characteristics.






Biogeographical Evidence studies the distribution of plants and animals in different places










throughout the world.( It is known as “Common Descent”) It hypothesis’ that specific species of










life took root in certain geographical areas and then spread out- but only were able to spread as

far as continent divisions allowed them to.

Anatomical evidence also supports common descent theory: it shows an explanation of

similarities anatomically and uses reason to support the theory.



Biochemical Evidence shows that all living organisms use the same identical basic biochemical

molecules, including DNA.


Intelligent Design: evolution is a theory based in science and evidence to support the theory.



Religious beliefs do not fit into the evolution theory but instead are based on faith. Faith based

creation is founded on creation started from God.

Natural Selection is a Darwinian theory used to describe a mechanism for adaptation. This

theory claims and has supportive evidence that states, “a species becomes suited to its

environment.”

Critical elements of natural selection are:

Variation- Individuals vary in physical appearance and can pass from generation to generation.
Competition for Limited Resources- Because of limited resources and competition for them

generational numbers remain about the same for particular species.

Adaptation- Advantageous traits are much more likely to be passed down generationally


because these particular traits can capture more of the resources.


Natural selection accounts for great diversity of life. Each and every organism is adapted and

designed for its particular way of life.






22.3 Classifications of Humans






Organisms are classified biologically by their evolutionary relatedness. “Binomial Name” of

organism gives it genus and also its species.

Same Domain refers to only general characteristics in common BUT those in the same “genus”

have A LOT of characteristics in common.

The three domain system used to classify (common ancestors)





(1) Bacteria





(2) Archaea





(3) Eukarya..






This classification shows that Archaea are closer to Eukarya than Bacteria.






DNA data is more commonly used and relied on today for species identification.






With DNA category classification scientists have determined that 2bya the domain Eukarya,










which consisted of a membrane-bound nucleus was the beginning of the category that humans










are in today (species Homo sapiens)






Primates are adapted to an arboreal life, which means living in trees.






Two sub-orders of primates are prosimians (lemurs tarsiers) and the anthropoids (monkeys,










apes, and humans)






Primate limbs are mobile and hand and feet have five digits.






Binocular Vision: snout is short so the eyes can move to the front of the head. Stereoscopic Vision










(depth perception is another characteristic, three different cone cells to differentiate the colors,










greens, blues, and reds.






Large Complex Brains are another characteristic of primaries.






Reduced Reproductive Rate: one birth at a time is normal in primates.






Human skeleton/Chimpanzee skeleton






Human = center spine exit






Ape= rear spine exit






Human= s-shaped spine






Ape= slight curved spine






Human= bowl shaped pelvis






Ape= Longer, narrow pelvis






Human= Inward at knees femur






Ape= Angle out femur






Human= Can hold weight on knees






Ape= Cannot hold much weight on knees























http://highered.mcgraw-hill.com/classware/infoCenter.do?isbn=0072986867



22.4 Evolution of Humanoids




The evolutionary tree shows that all primates originated from one common ancestor.



Humans and apes have been developing for approximately 7 mya.



Lineage is when to lines diverge from a common ancestor.



Bipedal posture is a feature that is hominid: another hominid feature is the face shape and the




brain size. There have been times when two or more hominids existed at the same time: such as




the Australopithecus robustus and the boisel and the Homo habillis.



Homo Erectus fossils are found in Africa, Asia, and Europe (1.9-.3 MYA) First to use fire.



Homosapiens (modern humans) evolved from erectus.



























evolution diagram from a google search from the internet





The Multiregional Continuity Hypothesis states that the development of homo sapiens in various






parts of the world was very similar. This theory is disputed by those who believe the “Out of




Africa Hypothesis” which claims that homo sapiens only evolved out of erectus from Africa and




THEN migrated to Europe and Asia.



The out of Africa hypothesis suggests that human beings today are much more characteristically




the same.



Neanderthals (H. neandertalenis) massive brow ridges and their nose, jaw, and teeth protruded.




Thought to have been taken over (supplanted) by homo sapiens. Had large brains, lived in caves,




culturally advanced.



Cro-Magnons- Oldest fossils to be labeled homo-sapiens-



Human Variation consist of what we call today ethnicity. These are believed to have evolved due to adaptations to local environmental conditions.



A modern DNA study finds that modern man has a common ancestry link between all world populations approximately one million years ago. This finding concludes that we as humans are closely related to one another.



Bioethical Focus -page 487



Passing on the culture from one generation to the next generation is called Bio-cultural Evolution




and this type of evolution is not dependent on genetics but to adaptation to one’s environment.



It began with homo habillis who we believe were tool makers; Farming is thought to have begun




about 10,000 years ago by the ancestors of today; Population increases in the society then may




have influenced the necessity of more agriculture to meet the needs of the people. The industrial




revolution began in the 18th century and cultural adaptations were continued to be passed down






to the generations of more recent history: Much of the progress and adaptations are harming




and even causing extinction to many number of species because they can not adapt to the




changes in the environment quickly enough. It is possible that extinction could be the result for




the human species if we do not learn how to and become willing to work within the biosphere


better.



Chapter 23/ Global Ecology and Human Interferences



23.1 The Nature of Ecosystems



23.2 Energy Flow



23.3 Global Biochemical Cycles




















http://highered.mcgraw-hill.com/classware/infoCenter.do?isbn=0072986867



23.1 The Nature of Ecosystems


The biosphere is where organisms are found on Earth. The entire biosphere can be considered a giant Ecosystem.


“Abiotic” components of an ecosystem are non-living.


“Biotic” components are living and can be categorized by their food source.


Autotrophs- inorganic nutrients and outside energy source are the only requirements.


Heterotrophs- need organic nutrient source. They are considered “consumers”.


Herbivores are animals that graze.


Csrnivores eat meat.


Omnivores eat both meat and also eat plants.


Detritus feeders- organisms that feed on detritus (decomposing particles of organic matter).
Niche- means the role of an organism.


Energy flow and chemical cycling= Solar energy (sun) produces energy which helps trees and

plant life (producers) grow which feeds the animals (consumers) which then is put back into the system by waste and decomposition which then turns into inorganic nutrient pool which then has full cycled and replenishes the nutrients for the “producers” plants and trees.


23.2 Energy Flow


There are interconnecting paths of energy represented in an ecosystems such as a forest.


Forest has a food web that has trophic relationships (feeding).


Diagrams that show single path of energy flow are known as food chains.


Example: (Grazing Food Chain)= leaves=caterpillars=birds=hawks


Detrital Food Chain=Detritus=earthworms=shrews


Ecological Pyramids


The length of a food chain is determined by the loss of energy between trophic levels.


The flow of energy with large losses between successive trophic levels is depicted as an ecological


pyramid. Energy losses between trophics result in pyramids based on organism numbers.


Biomass is the number of organisms multiplied by the weight of organic matter within one


organism.








http://highermagraw.hill.com draw
powerpoint for chapter

23.3 Global Biochemical Cycles


All organisms require both organic and inorganic materials.

Pathway for chemicals to circulate through ecosystems involve living (biotic) and non-living (geological/abiotic) components. These are known as biogeochemical cycles and can consist of gaseous material and sedimentary. A reservoir is an example of a chemical cycling.

The Water Cycle consists of evaporation, vaporized ware rises and falls as precipitation,
Water can also evaporated from plants (transpiration) gravity also eventually returns all fresh water to the sea, run off is water flowing directly into nearby streams, ground water can also be located in between layers of rock called aquifers.


The Carbon Cycle consist of organic matter (living and dead) to make up the reservoirs. Fossil fuels are the 300 mya remains of organic materials such as coal, oil, and natural gas.


CO2 along with other type gasses are being emitted because of human activities. Global warming and the Green house effect are two negative by products of human activity in our biosphere.


The Nitrogen Cycle


Plants cannot make use of nitrogen and nitrogen makes up approximately 78% of the Earth’s atmosphere.
Nitrogen fixation is the conversion of nitrogen into ammonium, which CAN be used by plants. Some cyan bacteria and free-living bacteria assist in this fixation process.
Some of the bacteria that help this process occur live in nodules on legume roots, such as beans, peas, and clover. They accomplish this by making available to host plants the nitrogen so they can produce the proteins and nucleic acids.
Production of nitrates during nitrogen cycle is called nitrification. It can occur by nitrogen gas turning into nitrate, from ammonium, nitrate producing bacteria and also assimilation (the process of plants taking up ammonia and nitrate from soil to use ions to make proteins and nucleic acids.

Denitrification is the process of conversion of nitrate back to nitrogen gas, which enters the atmosphere. Human activity interferes with the transfer rate significantly and poses a negative affect on our biosphere.

The Phosphorus Cycle

Phosphorus that has been trapped in oceanic sediments move onto land after a geological upheaval.

Slow weathering of rock puts up phosphate ions into the soil. Some of the phosphate material absorbs into the plant life that grows in the soil and then it is introduced into the animal life that ingests the plant life. The material is absorbed into their teeth and bone and takes a very long period of time to decompose back into the Earth. Some of the phosphate runs into the aquatic system. The phosphate that is then found in marine sediments does NOT become available to producers on land again until there is a geological upheaval.

Humans alter the ecosystem of the biosphere by mining, which boosts the supply of phosphates (fertilizers and production of detergents are two of the main culprits in the negative impact cycle)

Chapter 24/ Human Population, Planetary Resources, and Conservation

24.1 Human Population Growth

24.2 Human Use of Resources and Pollution

24.3 Biodiversity

24.4 Working Toward a Sustainable Society


24.1 Human Population Growth

Exponential growth refers to the number of reproducing humans increasing and then reproducing offspring.

Growth rate refers to the comparison of the number of births a year as compared to the number of deaths.

The Carrying Capacity refers to the maximum number of population that an environment can support.

MDC’s means the “More Developed Countries’ and the LDC’s refers to the “Less Developed Countries”.

MDC’s have experienced moderate growth in populations since the 1950’s. The USA has a higher than average population increase due to immigration and the baby boom between 1947 and 1964. There are still a large number of females within the child bearing age brackets.

LDC’s have lower death rates after WWII because of modern medicine. The birth rates in some countries is extremely high (5 offspring) and these two factors contribute greatly to the LDC’s high population numbers.

Replacement Population refers to when a couple reproduce only two off spring and no more.

24.2 Human Use of Resources and Pollution

Non-renewable resources are those that are limited in supply, such as, land, fossil fuels, and minerals.

Renewable resources can naturally be replenished such as, water, solar energy, harvested plants and animals for food.

A side effect of resource consumption is pollution, which is an undesirable alteration of the environment. Beach erosion is in part caused by humans living within close distance of the waters edge.

Desertification is the conversion of semiarid land to desert like conditions. It can be caused by humans allowing over grazing of lands.

Deforestation means the removal of trees. Soil loses its fertility and nutrients because of clearing of the natural foliage and trees.

Biodiversity can be loosed due to deforestation as humans often consume a food source from the deforested area that is now inhabited and the ecosystem that the animal lives within.

Water

Some areas of the USA and other places, exceed the renewable supply of water available and must then build dams or use aquifer systems to meet the needs of the populations in those areas.
Groundwater depletion is causing the settling of soil as it dries out, this is called subsidence. Withdrawal of groundwater can cause sink holes.

Saltwater intrusion is another consequence of aquifers. When the water table becomes low enough what usually was replenished by freshwater is then filled with saltwater. Saltwater intrusion reduces the available supply of freshwater along the coasts.

By 2025 2/3 of the world population may be living in areas that do not have enough fresh water supply to sustain the population. Countries and their governments must plan ahead and develop incentives for the people to work toward better water management and conservation measures.

Food

Food comes from three activities (1) growing crops (2) raising animals (3)fishing in the seas. Modern farming practices have increased the available food supply considerably but have also added some harmful practices as well:

(1) The planting of only a few (limited0 genetic varieties.
(2) Heavy use of fertilizers
(3) Generous irrigation
(4) Excessive fuel consumption

Intercropping is the farming practice of planting two or more different crops.
Soil degradation is occurring world wide. This means that the organic rich top soil is being eroded away.

Genetic Engineering: by altering plant genes genetically we may be causing more harm than good by the creation of super strain plants that actually draw more from the biosphere than they offset by the high yields and the amount of people that can be fed.

Domestic Livestock can add to the drain on resources and in high protein diet areas, such as the USA, much of the agricultural land is used for raising of livestock which uses up many of the non-renewable resources.

Energy

(Non-renewable Sources)
Nuclear power and also fossil fuel are both non-renewable energy sources and they make up approximately 81% of the types of energy we currently use to meet our energy needs.

Fossil fuels include: oil, natural gas, coal- they are derivatives of compressed remains of plants and animals that died thousands of years ago.

A person in an MDC uses in one day the amount of energy that A person in an LDC uses in a years time!

The burning of fossil fuels since 1850 has increase the level of carbon dioxide in the atmosphere considerably 9from 280 ppm up to 350 ppm) Greenhouse gasses include methane gas, carbon dioxide and other gasses released from the burning of fossil fuels. The Green house effect raises the temperature, which raises the water level because of the glacial melting.

Renewable Energy Sources- * include the following-

Hydropower- use falling water to convert to electricity through hydro-electric plants/ often used with large dams.

Geothermal- steam from energy conversion due to uranium, thorium, radium, and plutonium going through radioactive decay in the Earth.

Wind- wind power is believed to be used a lot more in the near future as an energy source/does not require as much land as some alternatives so this may be a better energy supplier.

Solar- Diffuse energy that must be collected, converted, and stored. Passive solar energy refers to such things as when a houses’ window faces the sun and the sunlight/energy enter the home and is stored .

Minerals are non-renewable raw materials that can be mined. These include fossil fuels, non-metallic raw materials (sand, gravel, phosphate). Many heavy metals are harmful to humans: such as, lead, mercury, arsenic, copper.

Surface mining of the Earth’s crust is one of the most negative types of activities that humans perform on the planet. The land becomes void of normal vegetation and also the rain run off then takes toxic waste into the streams and rivers and next the water supply.

Hazardous wastes refers to the build up of minerals which then leads to toxic/harmful levels being present to affect animals and humans in a variety of ways.








24.3 Biodiversity

“Variety of life on the planet Earth”

The loss of biodiversity is something that we face everyday. This includes habitat loss, alien species, pollution, over-exploitation, disease; which all lead to decline in natural species of specific area.

For a healthy balance in a particular ecosystem biodiversity is very important. This refers to the various species in an ecosystem all filling a particular function and niche in the system.

Medicines are an important by-product of biodiversity. Most of our drugs originated in living organisms.

Agriculture is highly affected by biodiversity and when certain crops fail for specific reasons more crops can be drawn from in the natural world of crops because there is a balance and diversity to the various kinds.

Bioethical Focus page 528

Discusses the intricate ecosystems in the coral reefs, which are often thought of as “underwater rain forests”. The ethical issue brought up in the article is the use of cyanide to catch the marine life found within the reefs. The ethical issue raised is the harmful effects of the cyanide to the ocean fish life, the actual changes in the reef and also to the humans who use the poison to catch the fish. Cyanide changes the entire environment and due to electron changes in the mitochondrial electrical impulse system, the entire eco system is damaged and altered for possibly thousands of years.

Biodiversity is a highly important resource. It is not just important for an individual species but when looking at the big picture it is even more important for the survival and adaptation of the entire ecosystem and even larger than that for the entire biosphere (earth).

Waste disposal is important, as is the availability of fresh water, as is the prevention of soil erosion, and the regulation of the climate helps shade and cool so the use of fans and air-
conditioning can be used less. What this all means is the human race overall must come to the awareness of the entire system working together in the biochemical cycles of nature so we do not run out of non-renewable resources and also we do not create more damage than can be overcome by the natural order of our planet.









24.4 Working Toward a Sustainable Society

In an ideal world we would always be able to provide the same amount of what we need and want as we do today as well as balancing biodiversity .

For a continuation of a sustainable society we must focus on not depleting our resources and also make efforts toward resource preservation. The LDC’s of the world create environmental
burdens and at the same time the MDC’s do the exact same thing.
Focusing on a natural ecosystem will be advantageous to us today as well as those generations of the future. We need to make use of our renewable resources and recycle what we use. Agriculture, business, preservation, pest management, mass transit, and energy efficiency are all ways we can address and help our environment.

Compendium Review Unit Four/ Major Topic One: Reproduction/ Chapters 16-17

Chapter 16/Reproductive System

16.1 Human Life Cycle

16.2 Male Reproductive 16.3 Female Reproductive System

16.4 Female Hormone Levels

16.5 Control of Reproduction

16.6 Sexually Transmitted Disease


16.1 Human Life Cycle

Male and females have quite different reproductive systems.

Sexual maturity is called puberty, it occurs in females a earlier, usually between ages 11-13 and in males, between 14-16.

Reproductive organs are called genitals.

Males-
(1) sperm is produced in testes
(2) sperm are transported in ducts and exit the male through the penis
(3)the penis delivers sperm to a females vagina
(4) testes produce sex hormones for masculization.

Females-
(1) eggs are produced within ovaries
(2)eggs are transported in uterine tubes to the uterus
(3) the vagina receives sperm from the male, transports menstrual flow out of the body, is the birth canal
(4) Fertilized eggs develop in the uterus, breasts produce milk for the newborn after birth.
(5) ovaries produce sex hormones for feminization and pregnancy.

Mitosis and Meiosis

Mitosis is “duplication division” of the 46 chromosomes within the nucleus.

Mitosis takes place in the life cycle of a human during times of growth and repair.

Meiosis is a type of cell division in humans that is referred to as “reduction division”.

It is very specific in its occurrence, in males it only takes place during the production of sperm and in females during production of eggs.

Meiosis reduces the chromosome count of 46 (diploid) in half to 23 (haploid).

In meiosis there are two cell divisions, called meiosis I and meiosis II.

The small flagellated sperm is specialized to carry chromosome to the egg. The egg is specialized in its waiting for sperm to bring chromosomes and also it provides cytoplasm as well as chromosomes.

The zygote ends up with 46 chromosomes because the sperm provides 23 and the egg provides 23.

Meiosis is the reason why the newly formed “zygote” ends up with 46 total chromosomes:
without meiosis, the zygote would end up with 92 chromosomes, 46 from the sperm and 46 from the egg.










16.2 Male Reproductive System

The primary sex organs in the male are the paired testes (gonads) suspended in sacs of the scrotum

The following are the male reproductive organs:

Testes- produce sperm/sex hormones

Epididymides-ducts for sperm storage and maturation

Vasa deferentia- conduct and store sperm

Seminal vesicles- contributes nutrients and fluid to semen

Prostrate gland- contributes fluid to semen

Urethra- conducts sperm

Bulbourethral glands- contribute mucus- containing fluid to semen

Penis- organ for sexual intercourse

Seminal fluid is made of ingredients that have functions toward reproduction.

Orgasm in Males:

Penis has long shaft with enlarged tip called glans penis, which is covered by foreskin, unless circumcision has taken place. Circumcision is the surgical removal of the foreskin, typically done when the male is still an infant.

During sexual arousal autonomic nerves release nitric oxide,NO. This stimulus leads to CGMP
production, next the smooth muscle walls relax, which leads to the erectile tissues to fill with
blood. An erection occurs because the blood vessels that carry blood away are compressed.

Erectile dysfunction occurs when the expansion of the penis is not enough to compress the veins.

Contractions expelling seminal fluid are part of male orgasm. Orgasm includes psychological and
physiological satisfaction. Refractory period is the time after orgasm when the penis returns to
normal size and there is a loss of sexual arousal. As a male ages the refractory period lengthens.
During ejaculation there may be up to 400 million sperm in semen.

The hypothalamus plays a vital role in sexual function because it secretes and regulates hormones.

Testosterone is the main male sexual hormone. It is responsible for normal development,
secondary sexual characteristics and greater muscular development.

16.3 Female Reproductive System

The female sexual organs include:

Ovaries-which produce eggs and hormones

Oviducts- which conduct eggs, location of fertilization (uterine or fallopian tubes)

Uterus (womb)- which houses the developing fetus

Cervix- is the opening to the uterus

Vagina- which receives the penis, serves as the birth canal and is the exit for menstrual flow.

Eggs are stored in the ovaries and when an egg is released it travels down the fallopian tube
toward the uterus. The egg can live approximately 6-24 hours and unless it becomes fertilized
(usually in the fallopian tube) by a sperm, then it does not become implanted in the uterine wall.
Implantation occurs when an egg becomes fertilized and then a zygote is formed.

An egg is usually released once a month, fertilization occurs in the oviduct (fallopian tube) and
development takes place in the uterus.

External female genitals are called the vulva. Included are two folds of skin called the labia
majora, labia minora, mons pubis, and clitoris, which is the female equivalent to the male penis,
as it is the organ of sexual arousal.

Orgasms in Females

Sexual stimulation occurs and the labia minora, vaginal wall and clitoris become engorged with
blood-the vagina expands and elongates, the vagina becomes lubricated. Orgasm occurs at
height of sexual response and the walls of the uterus contract rhythmically. Females require no
refractory (resting time) and can experience multiple orgasms in one sexual encounter.










16.4 Female Hormone Levels

Follicles are inside the ovary and each follicle contains an immature egg. Only a small number of the follicles are ever used during the reproductive years of a female because typically only one egg is released every month.

The ovarian cycle is as follows:

1-Primary follicle contains oocyte and produces estrogen

2-Secondary follicle contains secondary oocyte and produces estrogen and some progesterone

3-Graafian develops

4- Ovulation-secondary oocyte released

5-Corpus Luteum makes progesterone and some estrogen

6-Corpus Luteum degenerates

The hypothalamus controls the hormones responsible for sexual function in the female just like in the male.

Estrogen is responsible for secondary sex characteristics.

Estrogen and progesterone affect the uterus and breast development and also milk production.

The pelvic girdle is typically wider in females.

Menopause os when the ovarian cycle ceases in a woman’s life. Menstruation becomes irregular and then ceases.

Twenty-eight cycles of the Uterine Cycle are as follows:

Days 1-5/Low level of estrogen and progesterone

Days 6-13/increase production of estrogen

(Days 1-13) FSH secretion begins/follicle maturation occurs/estrogen secretion is prominent

Day 14/ ovulation usually occurs

(Day 14) LH spike occurs

Days 15-28/increase production of progesterone

(Day 15-28) LH secretion continues/corpus luteum forms/progesterone secretion is prominent.

Fertilization and Pregnancy

If an egg becomes fertilized with a sperm then the endometrium will receive the zygote and it becomes implanted in the lining.

The placenta sustains the developing embryo and later the fetus. It produces HCG/In time the placenta produces progesterone and some estrogen.












16.5 Control of Reproduction

Birth control is used to prevent pregnancies.

Abstinence is the best way and simply means to abstain from sex. Some other effective birth
control methods are: IUD, hormone skin patch, Depo-Provera, diaphragm, female condom, Male condom, and oral contraception.

The morning after pill is an emergency contraceptive and consists of four hormones, it blocks the progesterone receptor proteins and causes the bodily loss of the implanted embryo.

Infertility means the failure to achieve pregnancy.

Low sperm count or abnormal sperm can be cause, female obesity can cause.

Artificial Insemination can be used to implant sperm in female to impregnate egg.

In Vitro Fertilization can be used to conceive in laboratory and then implant within the female uterus.

Gamete Intrafallopian Transfer can be used and is more successful than IVF.

Surrogate Mothers, paid women usually to carry the parents sperm and egg.


16.6 Sexually Transmitted Disease

HIV- sexually transmitted disease (STD) AIDS is the last stage of the HIV virus.
38.6 million people are thought to be infected with HIV worldwide and 25 million people have died from AIDS.

HIV compromises the persons immune system and it is typically an opportunistic infection that kills the person, not the actual virus. There is no cure for AIDS but there is an antiretroviral therapy that can stop HIV reproduction.

Genital Warts-caused by HPV- often carriers do not show signs- genital warts are associated with cervical cancer and at this time there is a vaccine for warts which is exciting for the potential help with cervical cancer.

Genital Herpes- caused by the herpes simplex virus-Type I associated with cold sores/ Type II associated with genital herpes. Type II usually occurs during adulthood- Can cause neurological disorders in newborns and even lead to death.

Hepatitis- infects the liver, can lead to liver failure, cancer, and death.

There are 6 virus’ that cause hepatitis (A,B,C,D,E,G)

STD’s Caused by Bacteria

These types of sexually transmitted diseases can be cured with antibiotics.

Chlamydia/ infection of the lower reproductive tract.

Gonorrhea- in men a urethral discharge of thick, greenish-yellow. In men and women it leads to
pelvic inflammatory disease, can cause sterility in males.

Syphilis- has three stages, in third stage will cause death. When the bacteria crosses the placenta
it will cause blindness in the newborn.
Health focus on page 339
This article focuses on ways to avoid contracting STD’s. Abstinence is the best way to avoid any
STD’s. Multiple sex partners and choosing to have sex with people who have multiple sex
partners is risky. Bisexuals and homosexuals have higher rates of HIV virus in population so
protection and awareness are important. Unprotected sex with IV drug users is risky as is anal
sex.
Chapter 17/ Developing and Aging

17.1 Fertilization

17.2 Pre- Embryonic and Embryonic Development

17.3 Fetal Development

17.4 Pregnancy and Birth

17.5 Development After Birth

17.1 Fertilization

The union of a sperm and an egg is called fertilization. This union forms a zygote.

1- Sperm makes its way through the corona radiata.

2- Acrosomal enzymes digest a portion of zona pellucida.

3- Sperm binds to and fuses with egg plasma membrane.

4- Sperm nucleus enters cytoplasm of egg.

5- Cortical granules release enzymes; zona pellucida becomes fertilization membrane.

6- Sperm and egg pronulclei are enclosed in a nuclear envelope.

17.2 Pre- Embryonic and Embryonic Development














Computer generated imagery of DNA double-helix with methylation. The very beginnings of life-DNA :Genetic Blueprint







Processes of Development

Cleavage- the zygote begins to divide immediately after fertilization. Cell division is miotic and the zygote receives full set of chromosomes and genes.

Growth- Cell division increases in size of daughter cells.

Morphogenesis- Refers to shaping of the embryo and movement along with migration of certain cells.

Differentiation- Refers to specific structure and function of cells, which occurs first in the nervous system.

Extraembryonic Membranes are located outside the embryo. The function of the
Extraembryonic Membranes in human beings is specific to the species because humans develop in the uterus.

(1)Chorion- this is the fetal half of the placenta after development (the placenta is organ that nourishes and carries waste)

(2)Allantois- accumulates urine

(3)Yolk Sac- it is the first site of blood cell formation

(4)Amnion- contains fluids to cushion and protect

280 days is considered “normal gestation period” mathematically it is figured as: 280 days added to the start date of the last menstruation cycle.

Pre-embryonic Development- (first week) sperm enters egg and fertilization occurs in the fallopian tube…..as zygote moves along the oviduct cleavage occurs to produce morula, also the blast cyst forms and lodges into the lining of the uterus.

Embryonic Development-(second week till end of 8th week) the umbilical cord takes shape- gastrulayion begins
17.3 Fetal Development

Progesterone and estrogen are produced by the placenta during a pregnancy and these two
hormones along with negative feedback from the hypothalamus and pituitary no new follicles can
mature- the hormones also prevent any further menstruations during pregnancy.

Path of fetal blood travels through the umbilical cord. At the placenta there is an exchange of
molecules between fetal and maternal blood across the walls of the chorionic villi.


Science Focus page 362 / Cloning Humans: Can it be Done?

1997 was the first successful cloning experiment and although today we consider cloning of animals to be fairly commonplace, there are still a number of problems associated with it.
(1) A large number of the pregnancies are not successful because they do not end in full term live births.
(2) Abnormalities with the clone’s growth are common.
(3) Often spontaneous abortion occurs.
(4) Typical abnormalities occur.
(5) Appearance may look normal however disease and other difficulties soon arise often times.

There are two types of cloning:

Reproductive Cloning is when the end result is an individual-

Therapeutic Cloning is when the desired outcome is embryonic cells that can then be shaped genetically into various cell types.

Events of Fetal Development (3rd through the 9th month) During the 3rd and the 4th month

The fetus can be recognized as a human being. During this stage of development many changes are taking place with the fetus head development. During this stage it becomes possible to detect the sex of the fetus. The babies heartbeat becomes strong and can be detected with a stethoscope.

During the 5th through the 7th month

Movement can now be felt by the mother.
The fetus skin is covered by fine down (like fur).
Eyelids are open.
The baby stands a chance of survival if it is born at this time during the pregnancy.

During the 8th and the 9th month

Baby will be about 20 ½ inches long and weigh about 7 ½ lbs prior to birth. Head is usually pointed toward the cervix to emerge into the world head first through the birth canal. A baby born feet first is calle3d “breech’’.

The sex of a child is actually determined at the moment of fertilization. Males = chromosomes X+Y….Females = X+X

There is no way to differentiate the sex of a fetus externally during the first few weeks of pregnancy. If SRY genes are present in the genetic make up then the script is for male genitals but w/o SRY genes then the code is for female sex organs.


17.4 Pregnancy and Birth

Placental hormones (estrogen and progesterone) are responsible for physical changes of the mother during pregnancy. During pregnancy a woman goes through many physiological changes.
Energy level changes, body weight, nausea, and back pain.

Placental hormones in the mothers body support the growth and well being of the fetus. Some of the changes are: arteries relax, changes in blood pressure, blood volume increases, cardiac output increases, decrease in intestinal tract motility.

The pulmonary values increase and also, bronchial tubes relax, uterus size increases, and blood carbon dioxide levels drop significantly. Compression of the ureters and bladder can cause incontinence. Stretch marks often times occur.

Birth

Braxton Hicks Contractions are “false labor” contractions.

“Parturition” refers to the process of giving birth to offspring
Stage 1 Labor: the cervical canal disappears as the lower part of uterus is pulled upward toward the baby’s head when the uterus is contracting (this phase is called affacement) the baby’s head acts as a wedge- amniotic fluid usually ruptures during this stage-this stage is complete once the cervix dilates completely.

Stage 2 Labor: during this stage of labor the physical desire to push increases greatly as the contractions become stronger and also closer together. The baby travels down the birth canal and once the head emerges then the rest of the body follows more easily- the umbilical cord is cut once the baby starts breathing.

Stage 3 Labor: The placenta is delivered and then the birth cycle is complete.

17.5 Development After Birth

Aging refers to the continuation of development that naturally occurs in the life cycle and can lead to disease and death.

Gerontology is the study of aging.

Hypotheses of Aging

Genetic in Origin: It is believed that aging has a genetic basis/ defective mitochondrial (defective DNA polymere) may accelerate the process of aging.

Whole Body Process: A decline in the hormonal system function causes aging/diabetes type 2 and menopause occur in older adults because cell receptors are ineffective. The immune system does not function as well in older adults as it does in younger ones. Aging may or may not be caused by system failures. Cross linking of proteins that support tissues may increase the organ break down process and promote the aging process. Cross linking may also explain the inability of certain organs, such as the heart, lungs, and blood vessels to operate in latter life the same way that they operate in younger people. Elasticity in tendons and ligaments decreases with aging, which is another by product of cross linking.

Glucose attaching to the protein molecules in a persons body is the first step in cross linking.
Extrinsic Factors: It may come to light someday that the actual signs of aging are caused in large part to years and years in early life of lack of good diet and exercise.

Skin becomes thinner as people age.

The homeostasis system does not adjust to or tolerate heat in the older person.

Cardiovascular disease are leading cause of death in the older adult population.

Blood flow to liver is decreased as is the flow to the kidneys.

Loss of teeth is more due to neglect than to aging. Brain function for learning and retention is slower but still quite functional.

Loss of skeletal muscle is common, as is weight gain.

Friday, November 14, 2008

Ethical Issue: Unit Three/ Exercise... Is the Concept Working?

Unit Three; Ethical Issue/ Exercise … "Is the concept Working?"

Reading the article about reversing obesity by addressing environmental causes had some strong points. I agree with the statements about how culturally we have become a lot less physically active due to the close proximity of places and things that we use or go to in our daily lives. We, as a society have gotten used to walking from our houses to our vehicles and then just a few short steps to the store, the mall, or the movies. We rarely have to depend on our legs for transportation these days. Work has become much more sedantary for many people as compared to 30-40 years ago. Computers ,video games, televisions, even telephones, (which are now in everyones pocket instead of their desk or their wall) have all been contributers to a society that simply doesn't move any longer! The other item I agree with is the part about advertisements and commercialism for fast, convenient, high caloric, low nutritional food choices. The article also mentioned restaurants also being a leading cause of low nutritional, high caloric food intake. I don’t agree with more government involvement and regulations being the answer to the obesity problem in the US and many other parts of the world. I would love to see people get involved and get “Green” on themselves and their families and start doing different, healthier things in their lives.
In our text book the piece on exercise was informative. The advantages listed for even moderate exercise were stacked in complete favor of people getting off their couches and doing physical activities! I agree whole-heartedly with some of the positive outcomes for exercise. I believe that physical activity not only makes a person healthier by burning calories and exercising muscles, I also believe that exercise can prevent certain diseases and also help maintain better mental health by warding off depression and fatigue.
In conclusion, I think people of all ages need much more physical activity than what they are getting. I believe that if people would attempt to make even small changes in their physical activity just long enough to see some of the benefits, then they might be more apt to keep up the new behaviors and possibly even add more activities as time went on.

Unit Three Lab Project: Building a Movable Limb

Lab Project Unit Three; Build a Moveable Limb
Introduction:
My model is of a femur bone , which is the longest and also strongest bone in the body. The femur connects to the tibia. The muscle that is attached to the femur is the thigh muscle, but also the buttocks and hip muscles are in this same region of the lower body. My model shows and explains the workings and functions of the thigh muscle. The area I am focusing on is at the top of the femur. This is where the “lesser and greater trochanters are located and this is also where the muscle attaches and begins as it runs the length of the femur.

List of Limb Parts and Their Model Representation:




The parts to my model )from top to bottom)
Coxal Bone/includes ilium, pubis, ischium- I made them from construction paper and play dough-
Ace tabulum/head of femur, and “neck”- I made these from construction paper, magic marker, and play dough-
Greater and Lesser Trochanter- I made these from play dough-
Femur- I used a wooded spoon for the bone-
Medial Candyle /Lateral Epicondyle- I made these from Play dough-
Pantella (Kneecap) Construction paper
Tibial Tuberosity and Head of Fibula are made of Play dough
Tibia and the fibula are both represented by marker on construction paper-











These are my supplies I used for my project















This light blue poster has my femur bone /parts/ muscle theme all layed out:

The white poster board shows and explains a muscle cell and how it contracts due to actin/myosin filiments (cross-over). My second board also shows and explains about neurons that go to muscle cells that cause contraction. The second board shows the workings of a muscle fiber and a motor fiber and also on the cellular level how Calcium binds to Myosin sites.


Mydark blue poster board shows a Neuron /axon with Schwann Cells and the process of Action Potential.


Conclusion: My models show some of the most important processes within the muscular/nervous systems that help make our bodies so amazing. I have learned from working on this assignment that the CNS/PNS along with the other systems in the body are all connected through sensory communication and reactions.

Thursday, November 13, 2008

Online Lab: Leech Neurons

Leech Neurophysiology Lab:


http://www.leeches.biz/buy-leeches.htm web page of medicinal leeches


QUESTIONS ABOUT LEECH NEUROPHYSIOLOGY LAB:(Answer these questions to get full exemplary lab credit (A-level, 18-20 points)
1. What is the electrode measuring?

A-It is measuring the voltage of individual neurons.





2. Why use leeches in neurophysiology experiments?


Because it has been found that simple systems are easy to understand.
Simple nervous systems follow many of the same rules as more complex ones like
humans, so results that occur in the more simple systems may be directly relevant in
trying to understand the more complex human brain.
They are favored because of small number and large size of neurons.



3. What is the difference between a sensory and a motor neuron?

A sensory neuron is a nerve cell that transmits impulses to the central nervous system (spinal cord or brain). It is information such as taste, touch, hot, cold, sound, sight or pain. A motor neuron is a nerve cell that transmits direction to muscles and organs from the central nervous system to perform some function.

4. Do you think a leech experiences pain? What is pain?

A- No- First because it was anesthesized on the simulator prior to dissection. I also don’t think a leech experiences hardly any pain because they don’t have the “input region” of nerves to receive pain information signals plus they do not have brains that receive signals like humans do. They have no dendrites or synapses to relay pain messages like humans and many higher evolved species.

5. What were the two most interesting things about doing this lab?



A- I thought it was fun doing the mock dissection and also being able to check out the different electrical currents with the different tools.

6. Anything you found confusing or didn't like about the lab?

A- The only thing difficult was realizing I needed to play with it long enough to get familiar with the diiferent things it could do and what my lab requirements were for the project.

























Compendium Review Unit Three:Major Topic Two/ Movement










http://highered.mcgraw-hill.com/sites/dl/free/ image from our text book powerpoint








Chapter 11/Skeletal System



11.1 Overview of Skeletal System
11.2 Bone Growth, Remodeling, and Repair
11.3 Bones of the Axial Skeleton
11.4 Bones of the Appendicular Skeleton
11.5 Articulations



11.1 Overview of Skeletal System



Skeletal system consists of bones, cartilage, and fibrous connective tissue, which occurs in ligaments and joints-



The skeleton supports the body-



The skeleton protects soft body parts-



The skeleton produces blood cells-



The skeleton stores minerals and fat-



The skeleton, along with muscles, permits flexible body movement-



Anatomy of a long bone:



Diaphysis (shaft) is main portion-



Diaphysis has medullary cavity (walls contain compact bone)-



Medullary cavity filled with yellow bone marrow that stores fat-



Compact bone is highly organized- bone cells are called osteocytes and the ostescytes are in lacunae-



Matrix fills lacunae spaces-



Spongy bone is “unorganized’ when compared to compact bone- spaces of spongy bone are filled with red bone marrow which produces al types of blood cells-



Cartilage is not as strong as bone- it is flexible due to gel like matrix-cells of cartilage- these cells are called chondrocytes and are found irregularly in lacunae-



Cartilage does not have blood vessels, and is slow healing-



Three types of cartilage:



1-hyaline cartilage is firm somewhat flexible



2-fibrocartilage is stronger and matrix contains collagen fibers



3- elastic cartilage is flexible and matrix contains mostly elastin fibers



Fibrous connective tissue makes up the ligaments that connect bone to bone and bone to joint-



11.2 Bone Growth, Remodeling, and Repair



Bones ability to respond to stress by changing size, shape, and strength is called remodeling-



When bones are fractured and they repair this is called bone repair-



Bones are composed of living tissue- they are composed of several different types of cells-



1- Osteoblasts are bone forming cells



2- Osteocytes are mature bone cells



3- Osteoclasts are bone absorbing cells



Osteoclasts are removing matrix’ and osteoblasts are building it up-



Ossification is the formation of bone-



Intramembranous bones are flat bones such as skull bones-



Intramembranous ossification is the formation of bone between sheets of fibrous connective tissue-



Endochondral Ossification - most of the human skeleton falls into this type of bone-



Bone replaces the cartilaginous models of the bones- calcified bone matrix makes it possible for the endochondral bones to hold and support weight-



This process from cartilage to most long bone is as follows:



Cartilage model into the bone collar into the primary ossification center into the medullary cavity and secondary ossification sites and finally into the epiphyseal (growth) plate-



The epiphyseal contains four layers:



1- resting zone is where cartilage remains



2-proliferating zone is where chondrocytes produce new cartilage cells



3- degenerating zone cartilage cells dying off



4- ossification zone is where bone is forming



Bone length growth is final once the epiphyseal plate closes- hormones control the activity of the epiphyseal plate-



Hormones affect bone growth



Hormones are chemical messengers made in one part of the body but used by the body in another part.



Vitamin D is an important vitamin for bone formation because it is converted into a hormone that works in the intestinal tract with the absorption of calcium-



Bone Remodeling and its Role in Homeostasis



Osteoclasts is the break down of bone and Osteoblasts is the reforming process that is continually taking place within the body- This process is called “Remodeling”



Paget’s Disease is where the new bone is generated too quickly, therefore softer and weaker than desired-



Bone recycling allows our bodies to regulate the amount of calcium in the blood- blood calcium is important for clotting to occur-bones are the storage site for calcium-blood calcium is regulate by two hormones:



1- parathyroid hormone accelerates recycling and increases blood calcium level-



2- calcitonin hormone acts opposite to parathyroid hormone



Bone remodeling is the reason why our bones can respond to stress- exercise is strongly recommended as this also keeps bones strong by stimulating the osteoblasts instead of the osteoclasts process-



Bone Repair



The four steps to bone repair:



1-hematoma- after a fracture, blood escapes from vessels to form a hematoma in space between broken bones (6-8 hours)



2- fibrocartilaginous callus- tissue repair starts when a fibrocartilaginous callus fills space between ends of broken bones (approx. 3 weeks)



3- bony callus- osteoblasts produce trabeculae of spongy bone and convert fibrocartilaginous callus to bony callus- joins broken bones together (3-4 months)



4- remodeling- osteoblasts build new compact bone, osteoclasts absorb spongy bone, new medullary cavity is formed



Science Focus page 215



Identifying skeletal remains is discussed. Age of the remains can be approximated by dentition, which is studying the structure of the teeth. Bone ossification also gives clues to the approximate age of the remains. Pelvic bones are the best indicator of the gender. Observed racial characteristics can sometimes help determine the ethnicity of the skeleton, however, it is difficult with all of the genetic blending.



11.3 Bones of the Axial Skeleton




http://highered.mcgraw-hill.com/sites/dl/free image from our unit powerpoint presentation



There are 206 bones of the skeleton.



Axial skeleton lies in the midline of body- consists of skull, hyoid bone, vertebral column, and rib cage-



The skull formed by cranium and facial bones-



The cranium protects the brain- adults have 8 bones tightly joined together to form cranium- sinuses are contained in the cranium- major bones of the cranium are named like the lobes of the brain: frontal, parietal, occipital, temporal-



Facial bones mainly consist of the;



Mandible- lower jaw
Maxillae- bones that form upper jaw and hard palate
Zeugmatic- cheekbone prominences
Nasal bones- bridge of nose



The hyoid bone is the only skeletal bone that does not articulate with any other bone- it is attached to the temporal bones by muscles and ligaments and the larynx by a membrane-
The vertebral column consists of 33 vertebrae- it has four curvatures- when the vertebrae join this is how the column is formed- there are different types of vertebrae- they are named according to their location-



Cervical vertebrae are located in the neck (7)



Atlas is the name of the first vertebrae and is so named for the Greek god “Atlas”



Axis is number two and is named because it allows some rotation.



Thoracic vertebrae (12)
Ribs attach here
Lumbar (5)
These are the vertebrae in the small of the back.
Sacrum (5)
Fused vertebrae-form pelvic curvature
Coccyx (3-5)
Fused- form the tail bone
The rib cage is called the thoracic cage- composed of thoracic vertebrae- rib cage is part of the axial skeleton- rib cage is protective but flexible-rib is a flattened bone- there are 12 pairs of ribs- helps protect the heart and lungs-
The Sternum lies midline of the body- helps protect the heart and lungs- also called the breast bone- it is composed of three bones:



1-manubrium (the handle)
2- body (the blade)
3- xiphoid process (the point of blade)



11.4 Bones of the Appendicular Skeleton



Appendicular Skeleton consists of the bones within the pectoral and pelvic girdles and the attached limbs- pectoral girdle are specialized for flexibility and the pelvic girdle are specialized for strength-



The Pectoral Girdle and Upper Limb
The body has left and right pectoral girdles-



Each consist of:



scapula (shoulder blade)
clavicle (collar bone)
Glenoid cavity (allows arm to move in almost any direction)
Rotator cuff (tendons extend to humerous from four muscles on scalpula)
Humerous (long bone in the arm)
Radius (capitulum)
Ulna (trochlea)
Carpal (wrist consists of eight) look like small pebbles
Metacarpal (bones that fan out to form hand framework)
Digits (fingers or toes)
Phalanges (bones of fingers and thumbs)
The Pelvic Girdle and Lower Limb
The body has a left and right pelvic girdle
Pelvic girdle (hip girdle) has two heavy large coxal bones (hip bones)
Pelvis is a basin made of the pelvic girdle, sacrum, and coccyx-
Pelvis bears the body weight, protects organs within pelvic cavity, and is the place of attachment for legs-
Coxal bone (has three parts) 1-ilium 2-ischium 3-pubis- these are fused in adults
Hip socket (acetabulum) forms where three bones meet-
Femur )longest and strongest bone in the body)
Tibia
Patella (knee cap)
Fibula (slender bone of the leg)
Foot (each foot has ankle, instep, and five toes)
Ankle (consists of seven tarsal bones)
Instep has five elongated metatarsal bones
Phalanges (toe bones)



11.5 Articulations




http://highered.mcgraw-hill.com/sites/dl/free image from our unit powerpoint



Bones are joined at joints-



Joints are fibrous-



Suture are fibrous joints between the cranial bones and they are immovable-



Cartilaginous joints are connected by hyaline cartilage or fibro cartilage-



Cartilaginous joints tend to be slightly movable-



Synovial joint is one filled where the cavity is filled with lubricating fluid called synovial fluid- ligaments connect bone to bone and support/strengthen joints. The fluid sacs (synovial) ease friction and make movement possible-



Different types of Synovial joint movement:



1- flexion/Extension
2- Adduction/Abduction
3-Rotation/Circumduction
4- Inversion/Eversion

When there is muscle contraction, one bone moves in relation to another bone-



Chapter 12/Muscular System



12.1 Overview of Muscular System
12.2 Skeletal Muscle Fiber Contraction
12.3 Whole Muscle Contraction
12.4 Muscular Disorders
12.5 Homeostasis



12.1 Overview of Muscular System







All muscles contract-



When a muscle contracts, some part of the body moves.



Humans have three types of muscle tissue:



(1) smooth- fibers are spindle shaped cells-single nucleus (uninucleated)-cells arranged in parallel lines-located in walls of hollow internal organs- causes contractions, which are involuntary-slow to contract but can sustain longer- does not fatigue easily-



(2) cardiac- heart wall-fibers are uninucleated, striated, tubular, and branched-fibers interlock at intercalated disks-relax completely between contractions which prevent fatigue-rhythmical-occurs without outside nervous stimulation-involuntary-



(3) skeletal- fibers are tubular, multinucleated, and striated-attached to the skeleton-run length of muscle- often quite long-voluntary muscle-



Skeletal muscles have many functions:



1- support the body
2- help maintain constant body temperature
3-contraction assists movement in cardiovascular and lymphatic vessels
4-help protect internal organs and stabilize joints






Skeletal muscles are well organized



Whole muscle is made up of bundles of skeletal muscle fibers called fascicles



Fascicles are strands



Each fiber is surrounded by connective tissue as is the entire fascicle



Muscles are covered with fascia (type of connective tissue that becomes a tendon)



Skeletal muscles usually function in groups



For movement a group of muscles is stimulated, not just a single muscle-



Muscles contract and they shorten- this means that muscles can only pull, they cannot push-




Because of this muscles work in opposite pairs-



Human Muscle Groups from figure 12.4:



Front view-left side of picture



orbicular is oculi
orbicular is oris
Pectoralis major
Serratus anterior
External oblique
Quadriceps femoris
Tibialis anterior
Front view-right side of picture
Masseter
Deltoid
Biceps brachii
Rectus abdominis
Flexor carpi group
Adductor longus
Sartorius
Extensor digit rum longus





Back View:



Trapezius
Lattisimus dorsi
Triceps brachii
Extensor carpi group
Extensordigitorum
Gluteus maximus
Biceps femoris
gastrocnemius



12.2 Skeletal Muscle Fiber




http://highered.mcgraw-hill.com/sites/dl/free image from out powerpoint presentation
Skeletal muscles have alternating light and dark bands giving striated appearance-
A muscle fiber is a cell containing cellular components-



Plasma membrane is called sarcolemma



Cytoplasm is the sarcoplasm



Endoplasmic reticulum is the sarcoplasmic reticulum



Muscle fiber has T transverse tubules that penetrate/dip down into cell so they come into contact, but do not fuse together-



Sarcoplasmic reticulum encases myofibrils (which are the contractors in the muscle fibers)
There are thick and thin Myofilaments



Thick filaments- made of several hundred molecules of protein myosin



Thin filaments-consists of two intertwining strands of protein actin- two other proteins are also involved at this point, they are tropomyosin and troponin.



*See figure 12.5 page 233 for diagram



Sliding filaments- muscles are stimulated- impulses travel down T tubule- calcium is release- muscle fiber contracts as sarcomeres shorten-actin filaments slide past myosin (thick filament) and approach one another-band then shortens causing Z line to move inward- H zone almost completely disappears-



Movement of actin filaments in relation to myosin filaments is “sliding filament model”
Control of Muscle Fiber Contraction



Muscle fibers contract because they are stimulated by motor neurons with axons in the nerves-



Each axon has several branches-

Each branch ends in a terminal-

Synaptic Cleft is a small gap that separates axon terminal from sarcolemma-

Axon terminals consist of synaptic vesicles filled with neurotransmitter acetylcholine (ACh)-

ACh is released when nerve impulse travel down motor neuron and arrive at axon terminal-


ACh is released and quickly diffuses across the synaptic cleft and binds to receptors in sarcolemma-

12.3 Whole Muscle Contraction

Muscles have Motor Units

Axons within a nerve stimulate muscle fibers-

“motor unit” is a nerve fiber along with all of the muscle fibers it innervates-

A motor unit obeys the “All or Nothing” law-This occurs because muscle fibers in motor unit are stimulated all at once, so they all either contract or do not contract-

Muscle Twitch refers to a single contraction that lasts only a fraction of a second-

When a “motor unit” is rapidly stimulated it can respond to the next signal prior to complete relaxation in between-

Whole muscles contain many motor units-

“Recruitment” is when the intensity of nervous stimulation increases more motor units in muscle are activated-

Muscle tone is dependent on contraction and occurs in a person’s body when the motor units are contracted but not enough to cause movement-

Energy for Muscle Contraction

There are four (4) sources a muscle can get its energy from-
Two of the sources are stored in muscle-they are glycogen and fat (triglycerides)

Two are acquired from blood- muscles use “blood glucose” and “plasma fatty acids”

Muscle cells can store ATP but the amounts are limited.

There are three ways muscles can get more ATP

(1) produced by creatine phosphate (CP pathway) -ATP production by the CP pathway is the simplest and the fastest because it is only one reaction. The reaction occurs in the sliding filaments. Creatine Phosphate can ONLY be formed when a muscle cell is resting, and limited amount is stored.

(2) fermentation- produces two ATP from breakdown of glucose to lactate anaeroically-This process usually begins with glycogen. Hormones signal muscles cells to break down glycogen, which makes glucose available to the muscle- fermentation is fast acting but builds up lactate-lactate build up causes short term muscle pain- oxygen debt (taking in of oxygen) helps break down the excess lactate-
(3) cellular respiration (CR)- A molecule called myoglobin is present in muscle cells- this molecule combines with /stores oxygen-

ATP is not immediately supplied for muscle contraction-

ATP is supplied when a person exercises - submaximal (less than at maximum output) with high intensity-

Aerobic exercise utilizes “CR” to make ATP for muscle contraction and burns body fat-
“CR” uses glucose from glycogen, also uses fatty acids-


http://www.islandcounty.net/health/images/PhyAct1.jpg ( pyramid picture)


Health Focus page 238

Exercise benefit’s the entire body! It improves muscle strength, cardio respiratory endurance, body composition, prevents certain kinds of cancer, and improve bone density. Exercise relieves depression. Studies show that even moderate exercise for just a few hours a week improves a persons mental and physical health. No body is too old to benefit from physical activity.
Fast-twitch fibers are anaerobic, designed for strength- there motor units contain many fibers-provide explosions of energy- helpful in sports activities (sprinting, weight lifting, golf club swings)-light in color because fewer mitochondria-they have little myoglobin- rapidly gains maximum tension- greater tension- accumulate lactate easily due to dependence on anaerobic energy-

personal photo of the 2008 Whiskey Row Marathon in Prescott

Slow-twitch fibers have steadier tug, more endurance, small number of fibers- helpful in some sports (long distance running, biking, jogging, and swimming) energy is produced aerobically, they tire only when they are out of fuel- have many mitochondria- dark in color-contain myoglobin-surrounded by dense capillary beds and draw blood and oxygen from fast-twitch fibers-low maximum tension- highly resistant to fatigue- they have a substantial reserve of glycogen and fat, along with high mitochondria, help maintain and produce ATP when oxygen is available-

DOMS appears 24-48 hours after strenuous exercise -associated with activities where muscles contract while they are lengthening (walking down stairs, running down hill) prevention includes warm ups and cool downs, start new regimes slowly, don’t make huge changes in exercise program-

12.4 Muscular Disorders

Common Muscle Conditions

Spasms are sudden and involuntary

Strains are caused by stretching or tearing the muscle.

Tendinitis is when the tendon is impaired and inflamed.

Bursitis is the inflammation of the bursa.

Muscular Diseases

Myalgia means achy muscles usually caused by over-use or over-stretching.

Muscular Dystrophy is a progressive degeneration and weakening of the muscles.

Myasthenia gravis is an autoimmune disease of weakness in eye lids, face, neck, and extremities.

Amyotrophic Lateral Sclerosis (Lou Gehrig’s Disease) is gradual loss of abilities to walk, talk, chew, and swallow.

12.5 Homeostasis

Movement is essential in the maintaining of homeostasis. The skeletal and the muscular systems create movement by working together.

The skeletal and muscular systems work as a team with the following body systems to help maintain homeostasis:

(1)Cardiovascular system, (2)Urinary system,(3) Digestive system,(4) Nervous system, (5)Endocrine system,(6) Respiratory system, (7)Reproductive system.

The skeletal system protects soft organs of the body (1)brain (2)heart (3)lungs (4)spinal cord (5)kidneys (6)liver (7)endocrine glands

The muscular system pads bones and protects the abdominal organs-

Calcium homeostasis is over seen by the endocrine system as the skeletal system helps in the process.

Red bone marrow is where blood cells are produced.

Red blood cells are carriers of oxygen in blood.
Oxygen is necessary for production of ATP be aerobic CR. WBC originate in red bone marrow. White Blood Cells protect our bodies against pathogens. Bones have yellow and red marrow. Fat is stored in yellow bone marrow, that’s how and why its part of the bodies energy supply reserve.

Muscles Help Maintain Body Temperature

There are temperature sensitive neurons in the hypothalamus. ATP generates heat. Goose bumps are caused when arrector pili muscles contract.